The most brilliant minds should be directed to solving Earth's greatest challenges, such as climate change, says Sir David King.
The former UK chief scientist will use his presidential address at the BA Science Festival to call for a gear-change among innovative thinkers.
He will suggest that less time and money is spent on endeavours such as space exploration and particle physics.
He says population growth and poverty in Africa also demand attention.
"The challenges of the 21st Century are qualitatively different from anything that we've had to face up to before," he told reporters before the opening of the festival, which is being held this year in Liverpool.
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